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Before you jump into any anabolic‑cycling protocol it’s essential to do your homework.
A good starting point is the American College of Sports Medicine (ACSM) and the International Society of Sports Nutrition (ISSN) websites – both publish peer‑reviewed position statements on steroid use, safety, and training.
If you’re looking for real‑world experience, search forums such as Bodybuilding.com, Reddit’s r/bodybuilder or T3M2. Use keywords like:
"testosterone cycle 2024"
"post‑cycle therapy (PCT) best practices"
"side effects of testosterone enanthate"
Remember: filter out anecdotal posts that lack medical backing. A good rule of thumb is to cross‑check any claim against at least one reputable source.
3️⃣ How to Structure a Testosterone Enanthate Cycle
Below is a generic 10‑week cycle (2 weeks on, 8 weeks off) commonly used by intermediate lifters. This isn’t prescription medicine—consult a qualified healthcare professional before starting.
Week Dose (mg/week) Notes
1–2 200 mg 100 mg/bi‑weekly injections (e.g., Monday & Thursday).
3–4 300 mg 150 mg/bi‑weekly.
5–6 400 mg 200 mg/bi‑weekly.
7–8 0 mg Stop injection; plan for post‑cycle therapy (PCT).
Key points
Injection sites: Rotate between thighs, glutes, and abdomen to reduce local irritation.
Monitoring: Check liver enzymes, lipid profile, testosterone levels every 4 weeks.
Side effects: Water retention, gynecomastia, mood swings. Use a selective aromatase inhibitor (e.g., anastrozole) if estrogen rises.
2. Post‑Cycle Therapy (PCT)
After the final cycle day, you’ll need to restore natural testosterone production:
Medication Dose Duration
Clomiphene citrate (Clomid) 50 mg PO daily 5 days, then 25 mg for next 4–5 days
HCG (Human Chorionic Gonadotropin) 1,000 IU IM twice a week 2–3 weeks
How it works:
Clomiphene blocks estrogen receptors in the pituitary, stimulating LH/FSH release.
HCG mimics LH to maintain Leydig cell activity.
After ~6–8 weeks, repeat endocrine labs. If testosterone remains low (<300 ng/dL) or symptoms persist (fatigue, decreased libido), consider:
Option When to Consider Notes
Testosterone Replacement Persistent hypogonadism after 3–4 months of recovery attempts Can use transdermal gel, patches, or injections. Monitor PSA and hematocrit.
Consult Endocrinology Complex pituitary disease or refractory low testosterone Advanced testing (gonadotropin stimulation tests).
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5. Summary Checklist
Step Action Timing Notes
Baseline labs CBC, CMP, fasting glucose/insulin, HbA1c, lipid panel, TSH, free T4, LH/FSH, total and free testosterone (morning), estradiol, SHBG Day 0 Include cortisol if indicated
Insulin resistance assessment Calculate HOMA‑IR; consider OGTT/IGI Day 0
Hormone dynamics 8‑hour ACTH stimulation test; DHEA‑S measurement; baseline cortisol (if not done) Days 1–2
Imaging MRI pituitary if indicated by lab abnormalities As needed
Follow‑up labs Repeat fasting insulin & glucose after 3–6 months of lifestyle changes; recheck hormones if symptoms persist 3–6 months
Documentation Record all values, reference ranges, and clinical context Ongoing
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Key Points
Baseline metabolic testing (fasting insulin/glucose) is essential for identifying insulin resistance before proceeding to endocrine work‑up.
Hormonal assessment should focus on pituitary axis: ACTH, cortisol, LH/FSH, estradiol, IGF‑1.
- If abnormalities are found, proceed with dynamic testing (cosyntropin, GnRH stimulation) and imaging as needed.
Insulin resistance may coexist with endocrine disorders; treat metabolic derangements concurrently to improve overall health.
Follow-up: Reassess insulin sensitivity after any hormonal correction or after initiating therapy for underlying endocrine disorder.
By systematically addressing both the metabolic and endocrine components, this approach ensures that all contributing factors are identified and managed appropriately.
